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别名 TrkA (p-Y757), TrkA (p-Tyr757), p-TrkA (Y757), p-TrkA (Tyr757)
Anti-Phospho-TrkA (Tyr757) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-TrkA (Tyr757)。Anti-Phospho-TrkA (Tyr757) Polyclonal Antibody 可用于 IHC。
Anti-Phospho-TrkA (Tyr757) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-TrkA (Tyr757)。Anti-Phospho-TrkA (Tyr757) Polyclonal Antibody 可用于 IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,230 | 5日内发货 |
| 产品描述 | Anti-Phospho-TrkA (Tyr757) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr757). Anti-Phospho-TrkA (Tyr757) Polyclonal Antibody can be used in IHC. |
| 别名 | TrkA (p-Y757), TrkA (p-Tyr757), p-TrkA (Y757), p-TrkA (Tyr757) |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human brain tissue using Trk A (Phospho-Tyr757) antibody TMAC-04123 (left) or the same antibody preincubated with blocking peptide (right). ![]() |
| 应用 | IHC |
| 推荐剂量 | IHC: 1:50-100 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 性状 | Liquid |
| 缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | Peptide sequence around phosphorylation site of tyrosine 757 (E-V-Y(p)-A-I) derived from Human Trk A |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Actual: 87 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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