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Anti-KRT7 Antibody (7A324)
还可以产品编号 TMAY-00119
Anti-KRT7 Antibody (7A324) 是一种 Mouse 抗体，靶向 KRT7。Anti-KRT7 Antibody (7A324) 可用于 IHC-P。
Anti-KRT7 Antibody (7A324)
Anti-KRT7 Antibody (7A324)
还可以产品编号 TMAY-00119
Anti-KRT7 Antibody (7A324) 是一种 Mouse 抗体，靶向 KRT7。Anti-KRT7 Antibody (7A324) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-KRT7 Antibody (7A324) is a Mouse antibody targeting KRT7. Anti-KRT7 Antibody (7A324) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG3 |
| 克隆号 | 7A324 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human KRT7 in human breast carcinoma with mouse monoclonal antibody (1:50, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human KRT7 in human gastric cancer with mouse monoclonal antibody (1:50, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the center region of the Human KRT7 / Cytokeratin-7. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.1% BSA, pH 7.0 |
| 研究背景 | KRT7 (Keratin 7) is a Protein Coding gene. The protein encoded by this gene is a member of the keratin gene family. One AS, designated Homo sapiens keratin 7 (KRT7-AS), was selected due to its marked upregulation and concordant expression with its cognate sense counterpart, KRT7, in GC tissues and cell lines. KRT7-AS formed an RNA-RNA hybrid with KRT7 and controlled KRT7 expression at both the mRNA and the post-transcriptional levels. Moreover, forced overexpression of the KRT7-overlapping region (OL) of KRT7-AS (but not its non-KRT7-OL portions) increased keratin 7 protein levels in cells. Finally, forced overexpression of full-length KRT7-AS or OL KRT7-AS (but not its non-KRT7-OL regions) promoted GC cell proliferation and migration. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the center region of the Human KRT7 / Cytokeratin-7 |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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