购物车
- 全部删除
您的购物车当前为空
Anti-EphA2 Antibody (8N84)
还可以产品编号 TMAY-03368
Anti-EphA2 Antibody (8N84) 是一种 Rabbit 抗体，靶向 EphA2。Anti-EphA2 Antibody (8N84) 可用于 ELISA,FCM。
Anti-EphA2 Antibody (8N84)
Anti-EphA2 Antibody (8N84)
还可以产品编号 TMAY-03368
Anti-EphA2 Antibody (8N84) 是一种 Rabbit 抗体，靶向 EphA2。Anti-EphA2 Antibody (8N84) 可用于 ELISA,FCM。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-EphA2 Antibody (8N84) is a Rabbit antibody targeting EphA2. Anti-EphA2 Antibody (8N84) can be used in ELISA,FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8N84 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of Mouse EphA2 expression on MS1 cells. Cells were stained with purified anti-Mouse EphA2, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | ELISA,FCM |
| 推荐剂量 | ELISA: 1:5000-1:10000; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse EphA2 (rM EphA2; TMPY-01777; NP_034269.2; Met1-Asn535). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Eph receptor A2 (Ephrin type-A receptor 2 or EphA2) is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptors' corresponding family of ligands are the ephrins anchored to cell surfaces. The ephrins and Eph receptors are implicated as positional labels that may guide the development of neural topographic maps. They have also been found implicated in embryonic patterning, neuronal targeting, vascular development and adult neovascularization. The large family of ligands and receptors may make a major contribution to the accurate spatial patterning of connections and cell position in the nervous system. Furthermore, elevated expression of Eph receptors and ephrin ligands is associated with tumors and associated tumor vasculature, suggesting the Eph receptors and ephrin ligands also play critical roles in tumor angiogenesis and tumor growth. Unlike most Eph kinases, which are primarily expressed during development, EphA2 is primarily found in adult human epithelial cells. The cellular functions of EphA2 may be regulating cell growth, survival, migration, and angiogenesis.Unlike other receptor tyrosine kinases, ligand binding is not necessary for EphA2. Rather, the ligand appears to regulate EphA2 subcellular localization and its interactions with downstream adapter and signaling proteins. Eph receptor A2(EphA2) has been demonstrated to critically regulate tumor cell growth, migration and invasiveness. Eph receptor A2(EphA2) is frequently overexpressed and functionally altered in aggressive tumor cells, and that these changes promote metastatic character. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | FITC/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Mouse EphA2 protein (TMPY-01777) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-EphA2 Antibody (8N84) | purchase Anti-EphA2 Antibody (8N84) | Anti-EphA2 Antibody (8N84) cost | order Anti-EphA2 Antibody (8N84)
嗨！有任何问题？点我咨询
评论内容