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Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody

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Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody
产品编号 TMAC-01521
别名 p-FLT3 (Y842), p-FLT3 (Tyr842), FLT3 (p-Y842), FLT3 (p-Tyr842)

Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-FLT3 (Tyr842)。Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody 可用于 WB。

Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody

Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody
产品编号 TMAC-01521 别名 p-FLT3 (Y842), p-FLT3 (Tyr842), FLT3 (p-Y842), FLT3 (p-Tyr842)

Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-FLT3 (Tyr842)。Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FLT3 (Tyr842). Anti-Phospho-FLT3 (Tyr842) Polyclonal Antibody can be used in WB.
别名p-FLT3 (Y842), p-FLT3 (Tyr842), FLT3 (p-Y842), FLT3 (p-Tyr842)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of extracts from HepG2 cells treated with EGF using FLT3 (Phospho-Tyr842) Antibody TMAC-01521. The lane on the right is treated with the antigen-specific peptide.
应用
WB
推荐剂量
WB: 1:500~1:1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景FLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 842(S-N-Y(p)-V-V) derived from Human FLT3
抗原种属
human
Uniprot ID
P36888
化学信息
分子量Actual: 170 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pFLT3 (Y842)pFLT3 (Tyr842)FLT3 (pY842)FLT3 (pTyr842)FLT3 (phospho-Y842)FLT3 (phospho-Tyr842)

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