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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CSTF3 Polyclonal Antibody

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货号 TMAB-04735

Anti-CSTF3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CSTF3。Anti-CSTF3 Polyclonal Antibody 可用于 WB。

Anti-CSTF3 Polyclonal Antibody

Anti-CSTF3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04735

Anti-CSTF3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CSTF3。Anti-CSTF3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-CSTF3 Polyclonal Antibody is a Rabbit antibody targeting CSTF3. Anti-CSTF3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nuclear.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. Heterotrimeric CstF recognizes GU- and U-rich sequences located downstream of the polyadenylation site on RNA. CstF-77 (cleavage stimulation factor, 77 kDa subunit), also known as CstF3, is one of the three subunits comprising CstF. It can exist as a homodimer and functions as the bridge, directly interacting with the other two CstF subunits, namely CstF-64 and CstF-50. CstF-77 is highly conserved among eukaryotes. It contains an Alpha-helical structure with 11 HAT (Half-a-TPR-containing) repeats and is essential for CstF assembly. In addition, CstF-77 is capable of interacting with CPSF1 and FCP1, other factors involved in polyadenylation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CSTF3/CSTF77
抗原种属
Human
基因名称
CSTF3
基因ID
1479
蛋白名称
Cleavage stimulation factor subunit 3
Uniprot ID
Q12996
功能
CSTF3 (cleavage stimulation factor subunit 3) is required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs and is part of the CSTF complex. The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). CSTF3 functions as a homodimer and interacts directly with CSTF1 and CSTF2.
化学信息
分子量Theoretical: 83 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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