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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-LAIR1 Antibody (3K641)

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货号 TMAY-03527

别名 leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, CD305

Anti-LAIR1 Antibody (3K641) 是一种 Rabbit 抗体，靶向 LAIR1。Anti-LAIR1 Antibody (3K641) 可用于 ELISA。

Anti-LAIR1 Antibody (3K641)

Anti-LAIR1 Antibody (3K641)

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货号 TMAY-03527 别名 leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, CD305

Anti-LAIR1 Antibody (3K641) 是一种 Rabbit 抗体，靶向 LAIR1。Anti-LAIR1 Antibody (3K641) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-LAIR1 Antibody (3K641) is a Rabbit antibody targeting LAIR1. Anti-LAIR1 Antibody (3K641) can be used in ELISA.
别名leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, CD305
Ig Type
Rabbit IgG
克隆号
3K641
反应种属
Mouse
特异性
Mouse LAIR1
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LAIR-1 / CD305 (rM LAIR-1 / CD305; TMPY-02598; Q8BG84-1; Gln22-Ser133).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Leukocyte-associated Ig-like receptor-1 (LAIR1) is a surface molecule expressed on human mononuclear leukocytes that functions as an inhibitory receptor on human NK cells. In addition to NK cells, LAIR1 is expressed on T cells, B cells, macrophages, and dendritic cells. It is predicted to mediate inhibitory functions based on the presence of immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic domain. Cross-linking of LAIR1 on human T cell clones results in inhibition of cytotoxicity only in T cell clones that lack CD28 and can spontaneously lyse certain targets in vitro. Moreover, the cytolytic activity of freshly isolated T cells, which is thought to be mainly due to "effector" T cells, can be inhibited by anti-LAIR1 mAb. Thus, LAIR1 functions as an inhibitory receptor not only on NK cells but also on human T cells. This indicates that LAIR1 provides a mechanism of regulation of effector T cells and may play a role in the inhibition of unwanted bystander responses mediated by Ag-specific T cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse LAIR-1 / CD305 Protein (TMPY-02598)
抗原种属
Mouse
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

计算器

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关键词

LAIR1LAIR 1CD-305CD 305
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