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Anti-HMGCR Polyclonal Antibody
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产品编号 TMAB-00872
Anti-HMGCR Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HMGCR。Anti-HMGCR Polyclonal Antibody 可用于 WB。
Anti-HMGCR Polyclonal Antibody
Anti-HMGCR Polyclonal Antibody
还可以产品编号 TMAB-00872
Anti-HMGCR Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HMGCR。Anti-HMGCR Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-HMGCR Polyclonal Antibody is a Rabbit antibody targeting HMGCR. Anti-HMGCR Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 25 μg total protein per Lane of various lysates probed with HMGCR polyclonal antibody, unconjugated (TMAB-00872) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane. Peroxisome membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
| 免疫原 | KLH conjugated synthetic peptide: human HMGCR |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Metabolism of lipids and lipoproteins,Lipoprotein metabolism,Cholesterol Metabolism,Cholesterol Metabolism,Lipid metabolism,Lipoprotein metabolism,Heart disease,Lipid metabolism |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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