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Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody

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货号 TMAB-05216

Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DNA Polymerase delta, catalytic subunit。Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody

Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05216

Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DNA Polymerase delta, catalytic subunit。Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody is a Rabbit antibody targeting DNA Polymerase delta, catalytic subunit. Anti-DNA Polymerase delta, catalytic subunit Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases (1). In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches (2). Exonucleases involved in these processes include DNA polymerases, including DNA pol ∂ and é. DNA pol ∂ consists of two subunits, p125 which interacts directly with the sliding DNA clamp protein PCNA, and p50 (3,4). DNA pol ∂ can be regulated by cell cycle proteins (5). DNA pol é is a multiple subunit enzyme, the catalytic subunit of which is encoded by the POL2 gene (6,7). The exact reactions catalyzed by DNA pol ∂ and é on leading and lagging strands have not yet been elucidated.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DNA Polymerase delta, catalytic subunit
抗原种属
Human
基因名称
POLD1
基因ID
5424
蛋白名称
DNA polymerase delta catalytic subunit
Uniprot ID
P28340
功能
Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex.
化学信息
分子量Theoretical: 124 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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