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MAdCAM-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045235080.2.
MAdCAM-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045235080.2.


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| 产品描述 | MAdCAM-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045235080.2. |
| 生物活性 | Immobilized Cynomolgus MADCAM1, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-MADCAM1 Antibody, hFc Tag with the EC50 of 3.8 ng/ml determined by ELISA (QC Test). |
| 研究背景 | Mucosal addressin cell adhesion molecule–1 (MAdCAM-1) is an endothelial cell marker that is recognized by its ligands on lymphocytes: L-selectin and α4β7 integrin. MAdCAM-1 is highly expressed on intestinal endothelium and has, recently, been shown to play an important role in the development of acute GVHD in animal model. |
| 种属 | Cynomolgus |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | XP_0452350802 |
| 蛋白构建 | Gln22-Gln295 |
| 蛋白纯度 | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 内毒素 | < 1 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 30.65 kDa (Predicted); 55-65 kDa (Reducing condition, due to glycosylation) |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. 实际储存温度请以COA为准 |
对于不同动物的给药剂量换算,您也可以参考 更多