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FLT3 Ligand Protein, Mouse, Recombinant (CHO, His) is expressed in CHO Cells. The accession number is P49772.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 762 | 6-8日内发货 | |
| 10 μg | ¥ 1,260 | 6-8日内发货 | |
| 20 μg | ¥ 1,880 | 5日内发货 | |
| 50 μg | ¥ 3,230 | 5日内发货 |
| 生物活性 | ED 50 < 10.0 ng /ml, measured in a cell proliferation assay using AML5 cells. |
| 产品描述 | FLT3 Ligand Protein, Mouse, Recombinant (CHO, His) is expressed in CHO Cells. The accession number is P49772. |
| 种属 | Mouse |
| 表达系统 | CHO Cells |
| 标签 | His |
| 蛋白编号 | P49772 |
| 别名 | SL cytokine,Fms-related tyrosine kinase 3 ligand,Flt3LG,Flt3 ligand |
| 蛋白构建 | Gly27-Arg188 |
| 蛋白纯度 | > 95% as determined by SDS-PAGE |
| 分子量 | 24-30 kDa (Reducing conditions) |
| 内毒素 | < 0.2 EU/μg of protein as determined by the LAL method. |
| 缓冲液 | Lyophilized from a 0.2 μm filtered solution in PBS. |
| 复溶方法 | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 存储 | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Flt3L, also known as Fms-related tyrosine kinase 3 ligand and SL cytokine, is a single-pass type I membrane protein. It is expressed by stromal cells and T cells. Flt3L signals through tyrosine kinase receptor Flt3/Flk2 to stimulate the proliferation of early hematopoietic progenitor cells. It synergizes with other growth factors, such as GM-CSF, IL-3 and CSF, to promote the differentiation of both myeloid and lymphoid cells. Alternative splicing and proteolytic cleavage of membrane-bound Flt3L generates a soluble extracellular domain (ECD) isoform with full biological activity. |