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顶部生物活性储存和溶解信息计算器

Anti-RBBP4 Antibody (7R532)

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Anti-RBBP4 Antibody (7R532)
产品编号 TMAC-03552
别名 retinoblastoma binding protein 4, RBAP48, mRbAp48

Anti-RBBP4 Antibody (7R532) 是一种 Rabbit 抗体，靶向 RBBP4。Anti-RBBP4 Antibody (7R532) 可用于 WB,ICC,IHC,FCM,IP。

Anti-RBBP4 Antibody (7R532)

Anti-RBBP4 Antibody (7R532)

Rating icon 还可以
Anti-RBBP4 Antibody (7R532)
产品编号 TMAC-03552 别名 retinoblastoma binding protein 4, RBAP48, mRbAp48

Anti-RBBP4 Antibody (7R532) 是一种 Rabbit 抗体，靶向 RBBP4。Anti-RBBP4 Antibody (7R532) 可用于 WB,ICC,IHC,FCM,IP。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-RBBP4 Antibody (7R532) is a Rabbit antibody targeting RBBP4. Anti-RBBP4 Antibody (7R532) can be used in WB,ICC,IHC,FCM,IP.
别名retinoblastoma binding protein 4, RBAP48, mRbAp48
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of RbAP48 on different lysates using anti-RbAP48 antibody at 1/500 dilution. Positive control: Lane 1: NIH-3T3, Lane 2: Hela, Lane 3: Rat brain, Lane 4: Mouse testis.
2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-RbAP48 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-RbAP48 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-RbAP48 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-RbAP48 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-RbAP48 antibody. Counter stained with hematoxylin.
7. ICC staining RbAP48 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining RbAP48 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. ICC staining RbAP48 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
10. Flow cytometric analysis of Hela cells with RbAP48 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
ICC
IHC
FCM
IP
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; IP:1:10-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In the intact cell, DNA is closely associated with histones and other nuclear proteins to form chromatin.The remodeling of chromatin is believed to be a critical component of transcriptional regulation, and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation, and an increased accessiblity of DNA to transcription factors. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases. The retinoblastoma binding proteins RbAp46 and RbAp48 have been identified as histone binding proteins, and they are components of the histone deacetylase complex.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q09028
化学信息
分子量Theoretical: 48 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

RBAP-48RBAP 48

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