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Anti-gp130/IL6ST Antibody (2M306)

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产品编号 TMAY-03135

Anti-gp130/IL6ST Antibody (2M306) 是一种 Rabbit 抗体,靶向 gp130/IL6ST。Anti-gp130/IL6ST Antibody (2M306) 可用于 ELISA(Cap)。

Anti-gp130/IL6ST Antibody (2M306)

Anti-gp130/IL6ST Antibody (2M306)

Rating icon 还可以
产品编号 TMAY-03135

Anti-gp130/IL6ST Antibody (2M306) 是一种 Rabbit 抗体,靶向 gp130/IL6ST。Anti-gp130/IL6ST Antibody (2M306) 可用于 ELISA(Cap)。

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产品介绍

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产品描述
Anti-gp130/IL6ST Antibody (2M306) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (2M306) can be used in ELISA(Cap).
Ig Type
Monoclonal Rabbit IgG
克隆号
2M306
交叉反应
Mouse
应用
ELISA(Cap)
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL6ST / gp130 / CD130 (rM IL6ST / gp130 / CD130; TMPY-01832; NP_034690.3; Met1-Glu617).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively, spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1, and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse IL6ST / gp130 / CD130 Protein (TMPY-01832)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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