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Anti-M-CSF/CSF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 M-CSF/CSF1。Anti-M-CSF/CSF1 Polyclonal Antibody 可用于 WB。
Anti-M-CSF/CSF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 M-CSF/CSF1。Anti-M-CSF/CSF1 Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,175 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 | |
200 μL | ¥ 2,790 | 5日内发货 |
产品描述 | Anti-M-CSF/CSF1 Polyclonal Antibody is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit) |
验证活性 | Sample: Lung (Mouse) Lysate at 40 μg Primary: Anti-MCSF (TMAB-01120) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (secondary antibody) at 1/5000 dilution Predicted band size: 57 kDa Observed band size: 57 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cell membrane; Single-pass membrane protein. Processed macrophage colony-stimulating factor 1: Secreted, extracellular space. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Four distinct colony-stimulating factors (CSFs) that promote survival, proliferation and differentiation of bone marrow precursor cells have been well characterized: granulocyte macrophage CSF (GMCSF), granulocyte CSF (GCSF), macrophage CSF (MCSF), and Interleukin-3 (IL-3, Multi CSF). Both GMCSF and IL-3 are multipotential growth factors, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. In contrast, GCSF and MCSF are lineage restricted hematopoietic growth factors, stimulating final mitotic divisions and the terminal cellular maturation of the partially differentiated hematopoietic progenitors. Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF). |
免疫原 | KLH conjugated synthetic peptide: human MCSF/M-CSF |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Inflammatory mediators,CSFs,Cytokines and cytokine receptors ELISA kits |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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