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Anti-BCMA/TNFRSF17 Antibody (1M731)
还可以产品编号 TMAY-01036
Anti-BCMA/TNFRSF17 Antibody (1M731) 是一种 Rabbit 抗体，靶向 BCMA/TNFRSF17。Anti-BCMA/TNFRSF17 Antibody (1M731) 可用于 ELISA。
Anti-BCMA/TNFRSF17 Antibody (1M731)
Anti-BCMA/TNFRSF17 Antibody (1M731)
还可以产品编号 TMAY-01036
Anti-BCMA/TNFRSF17 Antibody (1M731) 是一种 Rabbit 抗体，靶向 BCMA/TNFRSF17。Anti-BCMA/TNFRSF17 Antibody (1M731) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-BCMA/TNFRSF17 Antibody (1M731) is a Rabbit antibody targeting BCMA/TNFRSF17. Anti-BCMA/TNFRSF17 Antibody (1M731) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1M731 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human BCMA / TNFRSF17 (rh BCMA / TNFRSF17; TMPY-04493; NP_001183.2; Met1-Ala54). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/BCMA/CD269 also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. TNFRSF17/BCMA/CD269 is a receptor for TALL-1 and BCMA activates NF-kappaB through a TRAF5-, TRAF6-, NIK-, and IKK-dependent pathway. The identification of TNFRSF17 as a NF-kappaB-activating receptor for TALL-1 suggests molecular targets for drug development against certain immunodeficient or autoimmune diseases. TNFRSF17/BCMA is a target of donor B-cell immunity in patients with myeloma who respond to DLI. Antibody responses to cell-surface BCMA may contribute directly to tumor rejection in vivo. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human BCMA / TNFRSF17 Protein (TMPY-04493) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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