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顶部生物活性储存和溶解信息计算器

Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2

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产品编号 TMAB-10684

Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Ezrin (Tyr146)。Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2

Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10684

Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Ezrin (Tyr146)。Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Ezrin (Tyr146). Anti-Phospho-Ezrin (Tyr146) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Human,Mouse (predicted:Rat,Dog,GuineaPig)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes. Microvillar peripheral membrane protein (cytoplasmic side).
组织特异性Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human Ezrin around the phosphorylation site of Tyr146
抗原种属
Human
基因名称
EZR
基因ID
7430
蛋白名称
Ezrin
Uniprot ID
P15311
功能
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
化学信息
分子量Theoretical: 69 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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