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Anti-CD28 Antibody-FITC (1N81) 是一种 FITC-conjugated Rabbit 抗体,靶向 CD28。Anti-CD28 Antibody-FITC (1N81) 可用于 FCM。
Anti-CD28 Antibody-FITC (1N81) 是一种 FITC-conjugated Rabbit 抗体,靶向 CD28。Anti-CD28 Antibody-FITC (1N81) 可用于 FCM。
产品描述 | Anti-CD28 Antibody-FITC (1N81) is a FITC-conjugated Rabbit antibody targeting CD28. Anti-CD28 Antibody-FITC (1N81) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1N81 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human CD28 expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human CD28. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
应用 | FCM |
推荐剂量 | 5 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD28 (rh CD28; P10747-1Met1-Pro152) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
偶联 | FITC |
其他可选修饰符 | Unconjugated/PerCP |
可提供抗体种类 | 3 |
免疫原 | Recombinant Human CD28 Protein |
抗原种属 | Human |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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