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Anti-CEACAM6 Antibody-PE (9T430)

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Anti-CEACAM6 Antibody-PE (9T430)
产品编号 TMAY-01221P
别名 NCA, CEAL, CEA, CD66c, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)

Anti-CEACAM6 Antibody-PE (9T430) 是一种 PE-conjugated Mouse 抗体,靶向 CEACAM6。Anti-CEACAM6 Antibody-PE (9T430) 可用于 FCM。

Anti-CEACAM6 Antibody-PE (9T430)
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Anti-CEACAM6 Antibody-PE (9T430)

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Anti-CEACAM6 Antibody-PE (9T430)
产品编号 TMAY-01221P 别名 NCA, CEAL, CEA, CD66c, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)

Anti-CEACAM6 Antibody-PE (9T430) 是一种 PE-conjugated Mouse 抗体,靶向 CEACAM6。Anti-CEACAM6 Antibody-PE (9T430) 可用于 FCM。

规格价格库存数量
25 T
¥ 680
5日内发货
100 T
¥ 890
5日内发货
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产品介绍

生物活性
产品描述
Anti-CEACAM6 Antibody-PE (9T430) is a PE-conjugated Mouse antibody targeting CEACAM6. Anti-CEACAM6 Antibody-PE (9T430) can be used in FCM.
别名NCA, CEAL, CEA, CD66c, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
Ig Type
Mouse IgG1
克隆号
9T430
交叉反应
Human
验证活性
Flow cytometric analysis of human CEACAM6 expression on human whole blood granulocytes. Human whole blood granulocytes were stained with PE-conjugated anti-Human CEACAM6. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
应用
FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM6 / CD66c (rh CEACAM6 / CD66c; TMPY-00971; NP_002474.4; Met1-Gly320) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated/APC
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human CEACAM6 / CD66c protein (TMPY-00971)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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