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顶部生物活性储存和溶解信息计算器

Anti-DIS3L2 Antibody (3M441)

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产品编号 TMAC-01149

别名 MGC42174, FLJ36974, DIS3-like exonuclease 2, Dis3l2, DIS3 mitotic control homolog like 2, DIS3 mitotic control homolog (S. cerevisiae) like 2, DIS3 L2, DI3L2_HUMAN

Anti-DIS3L2 Antibody (3M441) 是一种 Mouse 抗体，靶向 DIS3L2。Anti-DIS3L2 Antibody (3M441) 可用于 FCM,IHC,WB。

Anti-DIS3L2 Antibody (3M441)

Anti-DIS3L2 Antibody (3M441)

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Rating icon 还可以
产品编号 TMAC-01149 别名 MGC42174, FLJ36974, DIS3-like exonuclease 2, Dis3l2, DIS3 mitotic control homolog like 2, DIS3 mitotic control homolog (S. cerevisiae) like 2, DIS3 L2, DI3L2_HUMAN

Anti-DIS3L2 Antibody (3M441) 是一种 Mouse 抗体，靶向 DIS3L2。Anti-DIS3L2 Antibody (3M441) 可用于 FCM,IHC,WB。

规格价格库存数量
50 μL
¥ 1,985
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-DIS3L2 Antibody (3M441) is a Mouse antibody targeting DIS3L2. Anti-DIS3L2 Antibody (3M441) can be used in FCM,IHC,WB.
别名MGC42174, FLJ36974, DIS3-like exonuclease 2, Dis3l2, DIS3 mitotic control homolog like 2, DIS3 mitotic control homolog (S. cerevisiae) like 2, DIS3 L2, DI3L2_HUMAN
克隆号
3M441
交叉反应
Human
验证活性
1. Western blot analysis of DIS3L2 on human DIS3L2 recombinant protein using anti-DIS3L2 antibody at 1/1,000 dilution.
2. Western blot analysis of DIS3L2 on HEK293 (1) and DIS3L2-hIgGFc transfected HEK293 (2) cell lysate using anti-DIS3L2 antibody at 1/1,000 dilution.
3. Western blot analysis of DIS3L2 on Hela (1) and HepG2 (2) cell lysate using anti-DIS3L2 antibody at 1/1,000 dilution.
4. Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue using anti-DIS3L2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human bladder cancer tissue using anti-DIS3L2 antibody. Counter stained with hematoxylin.
6. Flow cytometric analysis of Jurkat cells with DIS3L2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用FCMIHCWB
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:100-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3' to 5' exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3' region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3' processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q8IYB7
化学信息
分子量Theoretical: 100 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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