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Anti-KLHDC4 Polyclonal Antibody

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货号 TMAB-08100

Anti-KLHDC4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KLHDC4。Anti-KLHDC4 Polyclonal Antibody 可用于 WB。

Anti-KLHDC4 Polyclonal Antibody

Anti-KLHDC4 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08100

Anti-KLHDC4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KLHDC4。Anti-KLHDC4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-KLHDC4 Polyclonal Antibody is a Rabbit antibody targeting KLHDC4. Anti-KLHDC4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景KLHDC4 is a 520 amino acid protein that contains six kelch repeats and exists as three alternatively spliced isoforms. The gene encoding KLHDC4 maps to human chromosome 16q24.2 and mouse chromosome 8 E1. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KLHDC4
抗原种属
Human
基因名称
KLHDC4
基因ID
蛋白名称
Kelch domain-containing protein 4
Uniprot ID
功能
Kelch proteins (and Kelch-like proteins) are proteins that have repeated kelch domains. Most Kelch proteins also have a BTB (defn) domain. Each kelch domain forms the blade of a propellar structure, with the repeated kelch domains forming a Beta-propellar. The structure of this Beta-propellar is known but the function is not characterised. KLHDC4 contains six Kelch repeats. There are three named isoforms.
化学信息
分子量Theoretical: 58 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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