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Anti-H2AFX Antibody (1G393) 是一种 Rabbit 抗体,靶向 H2AFX。Anti-H2AFX Antibody (1G393) 可用于 WB,ICC/IF,IHC,IP。
Anti-H2AFX Antibody (1G393) 是一种 Rabbit 抗体,靶向 H2AFX。Anti-H2AFX Antibody (1G393) 可用于 WB,ICC/IF,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-H2AFX Antibody (1G393) is a Rabbit antibody targeting H2AFX. Anti-H2AFX Antibody (1G393) can be used in WB,ICC/IF,IHC,IP. |
别名 | Histone H2AX, Histone H2A.X, H2AX, H2AFX, H2a/x |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of Histone H2A.X on MCF-7 cell lysates using anti-Histone H2A.X antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Histone H2A.X antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Histone H2A.X antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Histone H2A.X antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Histone H2A.X antibody. Counter stained with hematoxylin. 6. IF analysis of paraffin-embedded human pancreas tissue using anti-Histone H2A.X antibody (green). The nuclear counter stain is DAPI (blue). 7. IF analysis of paraffin-embedded mouse testis tissue using anti-Histone H2A.X antibody (green). The nuclear counter stain is DAPI (blue). 8. IF analysis of paraffin-embedded rat brain tissue using anti-Histone H2A.X antibody (green). The nuclear counter stain is DAPI (blue). |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:100-500; IP: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Histone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and human, and maps to chromosome 9 and 11q23, respectively. H2A.X meets from the other members of the H2A family by the presence of a highly conserved C-terminal motif. It is wide phosphorylated in response to ionizing radiation and plays an important role in the recognition and repair of DNA fragments are involved in the heavy chain constant region of cells involved in class switch recombination (CSR), a region-specific DNA reaction that replaces one immunoglobulin heavy chain constant region gene with another. The phosphorylated γ-H2A.X is also thought to firing new grades factors, including Rad50, Rad51 and BRCA1. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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