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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Rad51L1 Polyclonal Antibody

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货号 TMAB-12046

Anti-Rad51L1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Rad51L1。Anti-Rad51L1 Polyclonal Antibody 可用于 WB。

Anti-Rad51L1 Polyclonal Antibody

Anti-Rad51L1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12046

Anti-Rad51L1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Rad51L1。Anti-Rad51L1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Rad51L1 Polyclonal Antibody is a Rabbit antibody targeting Rad51L1. Anti-Rad51L1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in a wide range of tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Rad51L1
抗原种属
Human
基因名称
RAD51B
基因ID
5890
蛋白名称
DNA repair protein RAD51 homolog 2
Uniprot ID
O15315
功能
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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