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Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody

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货号 TMAB-10754

Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-GRLF1 (Tyr1087)。Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody

Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10754

Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-GRLF1 (Tyr1087)。Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GRLF1 (Tyr1087). Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human GRLF1 around the phosphorylation site of Tyr1087
抗原种属
Human
基因名称
ARHGAP35
基因ID
蛋白名称
Rho GTPase-activating protein 35
Uniprot ID
功能
Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.
化学信息
分子量Theoretical: 171 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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