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Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-GRLF1 (Tyr1087)。Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。
Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-GRLF1 (Tyr1087)。Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GRLF1 (Tyr1087). Anti-Phospho-GRLF1 (Tyr1087) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human) |
| 应用 | IHC-PIHC-FrIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human GRLF1 around the phosphorylation site of Tyr1087 |
| 抗原种属 | Human |
| 基因名称 | ARHGAP35 |
| 基因ID | |
| 蛋白名称 | Rho GTPase-activating protein 35 |
| Uniprot ID | |
| 功能 | Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor. |
| 分子量 | Theoretical: 171 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |