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Anti-Glypican 3 Antibody (8G714) 是一种 Rabbit 抗体,靶向 Glypican 3。Anti-Glypican 3 Antibody (8G714) 可用于 WB,FCM。
Anti-Glypican 3 Antibody (8G714) 是一种 Rabbit 抗体,靶向 Glypican 3。Anti-Glypican 3 Antibody (8G714) 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-Glypican 3 Antibody (8G714) is a Rabbit antibody targeting Glypican 3. Anti-Glypican 3 Antibody (8G714) can be used in WB,FCM. |
| Ig Type | IgG |
| 克隆号 | 8G714 |
| 反应种属 | Human |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 1:20-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane and Secreted, extracellular space. |
| 组织特异性 | Highly expressed in lung, liver and kidney. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
| 免疫原 | A synthesized peptide: human Glypican 3 |
| 抗原种属 | Human |
| 基因名称 | GPC3 |
| 基因ID | |
| 蛋白名称 | Glypican-3 |
| Uniprot ID | |
| 功能 | Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. |
| 分子量 | Theoretical: 65 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |