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Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ITGB2 (Ser756)。Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody 可用于 IHC-P,IF。
Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ITGB2 (Ser756)。Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody 可用于 IHC-P,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ITGB2 (Ser756). Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody can be used in IHC-P,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIF |
| 推荐剂量 | IHC-P: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human CD18 around the phosphorylation site of Ser756 |
| 抗原种属 | Human |
| 基因名称 | ITGB2 |
| 基因ID | |
| 蛋白名称 | Integrin beta-2 |
| Uniprot ID | |
| 功能 | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. |
| 分子量 | Theoretical: 82 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |