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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-C9orf72 Monoclonal Antibody (1M713)

Synonyms: FTDALS1, FTDALS, DENNL72, DENND9, ALSFTD
货号 TMAT-0197 一键复制产品信息
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Anti-C9orf72 Monoclonal Antibody (1M713) 是一种 Mouse 抗体，靶向 C9orf72。Anti-C9orf72 Monoclonal Antibody (1M713) 可用于 WB,IHC,IF,FCM。

Anti-C9orf72 Monoclonal Antibody (1M713)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0197

别名 FTDALS1, FTDALS, DENNL72, DENND9, ALSFTD

Anti-C9orf72 Monoclonal Antibody (1M713) 是一种 Mouse 抗体，靶向 C9orf72。Anti-C9orf72 Monoclonal Antibody (1M713) 可用于 WB,IHC,IF,FCM。

Anti-C9orf72 Monoclonal Antibody (1M713)
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产品介绍

生物活性
产品描述
Anti-C9orf72 Monoclonal Antibody (1M713) is a Mouse antibody targeting C9orf72. Anti-C9orf72 Monoclonal Antibody (1M713) can be used in WB,IHC,IF,FCM.
别名
FTDALS1, FTDALS, DENNL72, DENND9, ALSFTD
Ig Type
IgG2b
克隆号
1M713
反应种属
Human, Mouse, Monkey, Rat
应用WBIHCIFFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景The protein encoded by this gene plays an important role in the regulation of endosomal trafficking, and has been shown to interact with Rab proteins that are involved in autophagy and endocytic transport. Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778, 21944779). Studies suggest that hexanucleotide expansions could result in the selective stabilization of repeat-containing pre-mRNA, and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093). Alternative splicing results in multiple transcript variants encoding different isoforms.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human C9orf72 (AA: 110-199) expressed in E. Coli.
抗原种属
Human
基因名称
C9orf72
基因ID
203228
蛋白名称
Guanine nucleotide exchange C9orf72
Uniprot ID
Q96LT7
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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