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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CaIPLA2 Polyclonal Antibody

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货号 TMAB-03554

Anti-CaIPLA2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CaIPLA2。Anti-CaIPLA2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

Anti-CaIPLA2 Polyclonal Antibody

Anti-CaIPLA2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03554

Anti-CaIPLA2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CaIPLA2。Anti-CaIPLA2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-CaIPLA2 Polyclonal Antibody is a Rabbit antibody targeting CaIPLA2. Anti-CaIPLA2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Rabbit,Sheep)
应用WBIHC-PIHC-FrICC/IFIFELISA
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform LH-iPLA2: Membrane; Peripheral membrane protein. Note=Recruited to the membrane-enriched pseudopod upon MCP1/CCL2 stimulation in monocytes. Isoform SH-iPLA2: Cytoplasm.
组织特异性Four different transcripts were found to be expressed in a distinct tissue distribution.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010].
抗原信息
免疫原
KLH conjugated synthetic peptide: human CaIPLA2/PLA2G6
抗原种属
Human
基因名称
PLA2G6
基因ID
8398
蛋白名称
85/88 kDa calcium-independent phospholipase A2
Uniprot ID
O60733
功能
Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.
Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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