transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 5,180 | 5日内发货 | ||
500 μg | ¥ 20,700 | 5日内发货 | ||
1 mg | ¥ 34,600 | 5日内发货 |
产品描述 | transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-mFc-Avi |
蛋白编号 | P36897-1 |
别名 | TGFbetaRI, TGFBR1, ALK-5, SKR4, LDS2A, TGFB1R1, LDS1A, AAT5, tbetaR-I, TGF-bRI, tβR-I, ACVRLK4, TGF-beta RI, TGF-β RI, TGFR-1, TGFβRI |
蛋白构建 | Leu34-Glu125 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | 38.2 kDa (predicted). Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result. |
内毒素 | < 1 EU/μg by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. |
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TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated TGFbetaRI TGFBR1 ALK5 ALK-5 TGFBR 1 SKR4 TGFBR-1 LDS2A TGFB1R1 tbR-I ACVRLK 4 LDS1A AAT5 AAT-5 tbetaR-I TGF-bRI TGFbRI tβR-I SKR 4 AAT 5 TGFR 1 SKR-4 ACVRLK4 TGF-beta RI TGF-β RI ACVRLK-4 TGFR-1 ALK 5 TGF-b RI TGFβRI TGFR1 recombinant recombinant-proteins proteins protein