PIGR Protein, Human, Recombinant (S365G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69 kDa and the accession number is P01833.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,820 | 5日内发货 | ||
1 mg | ¥ 24,900 | 5日内发货 |
生物活性 | Measured by its binding ability in a functional ELISA.1. Immobilized rhhuman IgM at 2 μg/ml (100 μl/well) can bind biotinylated PIGR with a linear range of 0.94-15 ng/ml.2. When human human IgM is immobilized at 2 μg/ml (100 μl/well), PIGR inhibits 50% binding of biotinylated PIGR (0.062 μg/ml) at the concentration range of 0.03-20 μg/ml. |
产品描述 | PIGR Protein, Human, Recombinant (S365G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69 kDa and the accession number is P01833. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-His |
蛋白编号 | P01833 |
别名 | PIGR, FLJ22667, polymeric immunoglobulin receptor, MGC125362, MGC125361 |
蛋白构建 | extracellular domain (Met 1-Arg 638, 365 Ser/Gly) of Human PIGR (NP_002635.2) |
蛋白纯度 | > 97 % as determined by SDS-PAGE |
分子量 | 69 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR. |
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PIGR Protein, Human, Recombinant (S365G, His) FLJ-22667 MGC-125361 FLJ 22667 MGC-125362 MGC 125361 PIGR FLJ22667 MGC 125362 polymeric immunoglobulin receptor MGC125362 MGC125361 recombinant recombinant-proteins proteins protein