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Anti-IFNGR2 Antibody (8A302)
还可以产品编号 TMAY-03393
Anti-IFNGR2 Antibody (8A302) 是一种 Rabbit 抗体，靶向 IFNGR2。Anti-IFNGR2 Antibody (8A302) 可用于 ELISA。
Anti-IFNGR2 Antibody (8A302)
Anti-IFNGR2 Antibody (8A302)
还可以产品编号 TMAY-03393
Anti-IFNGR2 Antibody (8A302) 是一种 Rabbit 抗体，靶向 IFNGR2。Anti-IFNGR2 Antibody (8A302) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IFNGR2 Antibody (8A302) is a Rabbit antibody targeting IFNGR2. Anti-IFNGR2 Antibody (8A302) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8A302 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IFNGR2 (rM IFNGR2; TMPY-02122; NP_032364.1; Met1-Val243). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. IFNGR2 is a component of the IFNgamma receptor complex along with the IFNgammaR alpha chain (IFNGR1) and is a new Bax suppressor. The C-terminal fragment (cytoplasmic domain) of IFNgammaR2 is expressed in human cancer cell lines of megakaryocytic cancer (DAMI), breast cancer (MDA-MD-468), and prostate cancer (PC3 cells). The Th1 cytokine IFNgamma, acting through its heterodimeric receptors, IFNgammaR1 and IFNgammaR2, in the induction/proliferation of Th1 cells, might suppress the Th2 responses that may underlie atopic asthma. IFNGR2 has always been seen as a key mechanism for shielding T lymphocytes from the antiproliferative effects of the IFNgamma-signal transducer and activator of the transcription 1 (STAT1) pathway. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse IFNGR2 protein (TMPY-02122) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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