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CD204/MSR1 Protein, Mouse, Recombinant (His)

产品编号 TMPY-00528

别名: MSR, Scara1, macrophage scavenger receptor 1, MSR-A, Scvr, MRS-A, SR-AI, SR-AII

CD204/MSR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is AAH03814.1.

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CD204/MSR1 Protein, Mouse, Recombinant (His)

规格	价格/CNY		货期	数量
100 μg	￥ 3,820		5日内发货

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参考文献

生物活性	Testing in progress
产品描述	CD204/MSR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is AAH03814.1.

种属	Mouse
表达系统	HEK293 Cells
标签	N-His
蛋白编号	AAH03814.1
别名	MSR, Scara1, macrophage scavenger receptor 1, MSR-A, Scvr, MRS-A, SR-AI, SR-AII
蛋白构建	The Mouse MSR1 (AAH03814.1) extracellular domain (Trp 83-Val 354) was expressed, fused with a polyhistidine tag at the N-terminus.
蛋白纯度	> 90 % as determined by SDS-PAGE
分子量	32 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low-density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.

参考文献

1. Wang L. et al., 2003, Nat Genet. 35 (2): 128-9. 2. Chen Y.C. et al., 2008, Cancer Epidemiol Biomarkers Prev. 17 (4): 1001-3. 3. Shirato K. et al., 2009, Pflugers Arch. 459 (1): 93-103.Sun J. et al., 2006, Prostate. 66 (7): 728-37.

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Keywords

CD204/MSR1 Protein, Mouse, Recombinant (His) MSR Scara1 macrophage scavenger receptor 1 MSR-A Scvr MRS-A SR-AI SR-AII recombinant recombinant-proteins proteins protein

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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