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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-S100A8 Antibody (9G571)

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货号 TMAY-01681

别名 S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag

Anti-S100A8 Antibody (9G571) 是一种 Rabbit 抗体，靶向 S100A8。Anti-S100A8 Antibody (9G571) 可用于 IHC-P。

Anti-S100A8 Antibody (9G571)

Anti-S100A8 Antibody (9G571)

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Rating icon 还可以
货号 TMAY-01681 别名 S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag

Anti-S100A8 Antibody (9G571) 是一种 Rabbit 抗体，靶向 S100A8。Anti-S100A8 Antibody (9G571) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-S100A8 Antibody (9G571) is a Rabbit antibody targeting S100A8. Anti-S100A8 Antibody (9G571) can be used in IHC-P.
别名S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag
Ig Type
Rabbit IgG
克隆号
9G571
反应种属
Human
特异性
Human S100A8
验证活性
1. Immunochemical staining of human S100A8 in human tonsil with rabbit monoclonal antibody at 1:20000 dilution, formalin-fixed paraffin embedded sections.
2. Immunochemical staining of human S100A8 in human breast carcinoma with rabbit monoclonal antibody at 1:20000 dilution, formalin-fixed paraffin embedded sections.
应用IHC-P
推荐剂量
IHC-P: 1:2000-1:50000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human S100A8 (rh S100A8; TMPY-01356; NP_002955.2; Met1-Glu93).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of S100A8 protein is associated with various diseases and cancers. S100A8 may have an immunoregulatory role by contributing to the regulation of fetal-maternal interactions. It may play a protective role and its absence may allow infiltration by maternal cells, a process eventually manifesting as resorption. The heterodimeric S100 protein complex S100A8/A9 which has been shown to be involved in inflammatory and neoplastic disorders. The complex can induce cell proliferation, or apoptosis, inflammation, collagen synthesis, and cell migration. S100A8/A9 has emerged as important pro-inflammatory mediator in acute and chronic inflammation. More recently, increased S100A8 and S100A9 levels were also detected in various human cancers, presenting abundant expression in neoplastic tumor cells as well as infiltrating immune cells. On the one hand, S100A8/A9 is a powerful apoptotic agent produced by immune cells, making it a very fascinating tool in the battle against cancer. It spears the risk to induce auto-immune response and may serve as a lead compound for cancer-selective therapeutics. In contrast, S100A8/A9 expression in cancer cells has also been associated with tumor development, cancer invasion or metastasis. Altogether, its expression and potential cytokine-like function in inflammation and cancer suggest that S100A8/A9 may play a key role in inflammation-associated cancer.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human S100A8 Protein (TMPY-01356)
抗原种属
Human
研究领域
Calcium-binding Proteins and Related Molecules
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

计算器

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