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PRPS2 Protein, Human, Recombinant (His)
产品编号 TMPY-04768
PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine stretch.
PRPS2 Protein, Human, Recombinant (His)
产品编号 TMPY-04768
PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine stretch.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μg | ¥ 2,530 | 5日内发货 |
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产品信息
| 生物活性 | Kinase activity untested |
| 产品描述 | PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine stretch. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | C-His |
| 蛋白编号 | P11908-1 |
| 别名 | PRSII,PRPS2,phosphoribosyl pyrophosphate synthetase 2 |
| 蛋白构建 | A DNA sequence encoding the human PRPS2 (P11908-1) (Met1-Leu318) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Met |
| 蛋白纯度 | > 95 % as determined by SDS-PAGE |
| 分子量 | 35.6 kDa (predicted); 36 kDa (reducing conditions) |
| 内毒素 | Please contact us for more information. |
| 缓冲液 | Supplied as sterile PBS, pH 7.4. |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 存储 | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. |
| 研究背景 | PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine stretch. |
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