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Anti-Jagged 1 Antibody-PE (7Z938)
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产品编号 TMAY-01963P
别名 JAGL1, Jagged 1, HJ1, CD339, AWS, AHD, AGS
Anti-Jagged 1 Antibody-PE (7Z938) 是一种 PE-conjugated Mouse 抗体，靶向 Jagged 1。Anti-Jagged 1 Antibody-PE (7Z938) 可用于 FCM。
Anti-Jagged 1 Antibody-PE (7Z938)
331 Anti-Jagged 1 Antibody-PE (7Z938)
还可以产品编号 TMAY-01963P 别名 JAGL1, Jagged 1, HJ1, CD339, AWS, AHD, AGS
Anti-Jagged 1 Antibody-PE (7Z938) 是一种 PE-conjugated Mouse 抗体，靶向 Jagged 1。Anti-Jagged 1 Antibody-PE (7Z938) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 T | ¥ 685 | 5日内发货 | |
| 100 T | ¥ 885 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Jagged 1 Antibody-PE (7Z938) is a PE-conjugated Mouse antibody targeting Jagged 1. Anti-Jagged 1 Antibody-PE (7Z938) can be used in FCM. |
| 别名 | JAGL1, Jagged 1, HJ1, CD339, AWS, AHD, AGS |
| Ig Type | Mouse IgG2a |
| 克隆号 | 7Z938 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-JAG1(CD339) reactivity on HepG2 cells analyzed by flow cytometry. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAG1 / Jagged 1 (rh JAG1 / Jagged 1; TMPY-01475; NP_000205.1; Met1-Ser1046) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Protein Jagged 1, also known as JAG1, JAGL1, and CD339, is a single-pass type I membrane protein that contains 1 DSL domain and 15 EGF-like domains. JAG1/Jagged 1 is widely expressed in adult and fetal tissues. The expression of JAG1/Jagged 1 is up-regulated in cervical squamous cell carcinoma. JAG1/Jagged 1 is also expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells. JAG1/Jagged 1 is a ligand for multiple Notch receptors. It is involved in the mediation of Notch signaling. JAG1/Jagged 1 may be involved in cell-fate decisions during hematopoiesis. JAG1/Jagged 1 seems to be involved in the early and late stages of mammalian cardiovascular development. It inhibits myoblast differentiation and enhances fibroblast growth factor-induced angiogenesis. Defects in JAG1/Jagged 1 are the cause of Alagille syndrome type 1 (ALGS1). Alagille syndrome is an autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations. Defects in JAG1/Jagged 1 are also a cause of tetralogy of Fallot (TOF). TOF is a congenital heart anomaly that consists of pulmonary stenosis, ventricular septal defect, dextroposition of the aorta (aorta is on the right side instead of the left), and hypertrophy of the right ventricle. This condition results in a blue baby at birth due to inadequate oxygenation. |
| 偶联 | PE |
| 免疫原 | Recombinant Protein: Human JAG1 / Jagged 1 protein (TMPY-01475) |
| 抗原种属 | Human |
| 研究领域 | Notch Pathway |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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