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Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2

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产品编号 TMAB-10456

Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Cdc25B (Ser149)。Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 可用于 WB。

Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2

Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10456

Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Cdc25B (Ser149)。Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,960
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200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Cdc25B (Ser149). Anti-Phospho-Cdc25B (Ser149) Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
交叉反应
Mouse (predicted:Human,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human Cdc25B around the phosphorylation site of Ser149
抗原种属
Human
基因名称
CDC25B
基因ID
994
蛋白名称
M-phase inducer phosphatase 2
Uniprot ID
P30305
功能
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
化学信息
分子量Theoretical: 65 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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