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DSG3 Protein, Human, Recombinant (His)

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货号 TMPK-00871

别名 SG3, PVA, DSG-3, DSG3, Desmoglein-3, CDHF6

To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64 kDa and the accession number is P32926.

DSG3 Protein, Human, Recombinant (His)
其他形式的 “DSG3 Protein, Human, Recombinant (His)”:
DSG3 Protein, Mouse, Recombinant (His)
DSG3 Protein, Human, Recombinant (E. coli, His)
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PVA (Mw 61000)
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PVA (Mw 145000)
PVA (Mw 27000)
PVA (Mw 205000)
PVA (Mw 195000)
PVA (Mw 47000)
PVA (Mw 130000)
PVA (Mw 67000)

DSG3 Protein, Human, Recombinant (His)

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
货号 TMPK-00871 别名 SG3, PVA, DSG-3, DSG3, Desmoglein-3, CDHF6

To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64 kDa and the accession number is P32926.

规格价格库存数量
5 μg
¥ 313
3日内发货
10 μg
¥ 498
3日内发货
20 μg
¥ 793
3日内发货
50 μg
¥ 1,580
3日内发货
100 μg
¥ 2,660
现货
200 μg
¥ 4,790
5日内发货
500 μg
¥ 10,600
5日内发货
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浓度: 1.02 mg/mL
纯度: > 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64 kDa and the accession number is P32926.
生物活性
Immobilized Human DSG3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-DSG3 Antibody, hFc Tag with the EC50 2.1ng/ml determined by ELISA.
研究背景
To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.
种属
Human
表达系统
HEK293 Cells
标签C-His
蛋白编号P32926
蛋白构建Glu50-Arg615
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名SG3, PVA, DSG-3, DSG3, Desmoglein-3, CDHF6
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量64 kDa (predicted). Due to glycosylation, the protein migrates to 70-75 kDa based on Tris-Bis PAGE result.
颜色Transparent
物理性状Liquid
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

SG-3SG 3DSG 3CDHF-6CDHF 6
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