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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NEK3 Polyclonal Antibody

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货号 TMAB-09346

Anti-NEK3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NEK3。Anti-NEK3 Polyclonal Antibody 可用于 WB。

Anti-NEK3 Polyclonal Antibody

Anti-NEK3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09346

Anti-NEK3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NEK3。Anti-NEK3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-NEK3 Polyclonal Antibody is a Rabbit antibody targeting NEK3. Anti-NEK3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm (By similarity). Cell projection, axon (By similarity).
组织特异性Up-regulated in malignant versus normal breast tissue. Isoform 2 shows a high level of expression in testis, ovary and brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar2009].
抗原信息
免疫原
KLH conjugated synthetic peptide: human NEK3
抗原种属
Human
基因名称
NEK3
基因ID
4752
蛋白名称
Serine/threonine-protein kinase Nek3
Uniprot ID
P51956
功能
Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.
化学信息
分子量Theoretical: 58 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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