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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CYP1B1 Polyclonal Antibody

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货号 TMAB-04872

Anti-CYP1B1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP1B1。Anti-CYP1B1 Polyclonal Antibody 可用于 WB。

Anti-CYP1B1 Polyclonal Antibody

Anti-CYP1B1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04872

Anti-CYP1B1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP1B1。Anti-CYP1B1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-CYP1B1 Polyclonal Antibody is a Rabbit antibody targeting CYP1B1. Anti-CYP1B1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane. Microsome membrane.
组织特异性Expressed in many tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cytochrome P450 1B1 is a key enzyme involved in the production of potentially carcinogenic estrogen metabolites and the activation of environmental carcinogens and is the predominant member of the CYP1 family expressed in normal breast tissue and breast cancer. Estrogen has been proposed to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol estrogen (CE). CYP1B1 catalyzes the conversion of 17-beta-estradiol to the catechol estrogen metabolites 2-OH-E2 and 4-OH-E2 which have both been postulated to be involved in mammary carcinogenesis. Genetic polymorphisms in CYP1B1 may play an important role in human prostate carcinogenesis as well. Polymorphism of the CYP1B1 gene at codon 432 (Val-->Leu) is associated with a change in catalytic function.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CYP1B1
抗原种属
Human
基因名称
CYP1B1
基因ID
1545
蛋白名称
Cytochrome P450 1B1
Uniprot ID
Q16678
功能
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Participates in the metabolism of an as-yet-unknown biologically active molecule that is a participant in eye development.
化学信息
分子量Theoretical: 61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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