购物车
- 全部删除
您的购物车当前为空
Anti-TNFR2/CD120b/TNFR1B Antibody (8M527)
还可以产品编号 TMAY-03124
Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) 是一种 Rabbit 抗体，靶向 TNFR2/CD120b/TNFR1B。Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) 可用于 ELISA(Cap)。
Anti-TNFR2/CD120b/TNFR1B Antibody (8M527)
Anti-TNFR2/CD120b/TNFR1B Antibody (8M527)
还可以产品编号 TMAY-03124
Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) 是一种 Rabbit 抗体，靶向 TNFR2/CD120b/TNFR1B。Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) 可用于 ELISA(Cap)。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) is a Rabbit antibody targeting TNFR2/CD120b/TNFR1B. Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8M527 |
| 交叉反应 | Mouse |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TNFR2 / TNFRSF1B / CD120b (rM TNFR2 / TNFRSF1B / CD120b; TMPY-01697; NP_035740.2; Met1-Gly258). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFRSF1B is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. TNFR2/CD120b/TNFRSF1B is not a major contributing factor to the genetic risk of type 2 diabetes, its associated peripheral neuropathy and hypertension and related metabolic traits in North Indians. Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B) has been reported to be associated with SLE risk in Japanese populations. TNFR2/CD120b/TNFRSF1B serves as a receptor with high affinity for TNFSF2 and approximately 5-fold lower affinity for homotrimeric TNFSF1. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse TNFR2 / TNFRSF1B / CD120b Protein (TMPY-01697) |
| 抗原种属 | Mouse |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) | purchase Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) | Anti-TNFR2/CD120b/TNFR1B Antibody (8M527) cost | order Anti-TNFR2/CD120b/TNFR1B Antibody (8M527)
嗨！有任何问题？点我咨询
评论内容