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Anti-GPR124 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 GPR124。Anti-GPR124 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。
Anti-GPR124 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 GPR124。Anti-GPR124 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-GPR124 Polyclonal Antibody 2 is a Rabbit antibody targeting GPR124. Anti-GPR124 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit,Sheep) |
| 应用 | WBIHC-PIHC-FrICC/IFIFELISA |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies. |
| 免疫原 | KLH conjugated synthetic peptide: human GPR124 |
| 抗原种属 | Human |
| 基因名称 | ADGRA2 |
| 基因ID | |
| 蛋白名称 | Adhesion G protein-coupled receptor A2 |
| Uniprot ID | |
| 功能 | Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube. |
| 分子量 | Theoretical: 139 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |