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Anti-GPR124 Polyclonal Antibody 2

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货号 TMAB-06689

Anti-GPR124 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 GPR124。Anti-GPR124 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

Anti-GPR124 Polyclonal Antibody 2

Anti-GPR124 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-06689

Anti-GPR124 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 GPR124。Anti-GPR124 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,960
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200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-GPR124 Polyclonal Antibody 2 is a Rabbit antibody targeting GPR124. Anti-GPR124 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrICC/IFIFELISA
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GPR124
抗原种属
Human
基因名称
ADGRA2
基因ID
蛋白名称
Adhesion G protein-coupled receptor A2
Uniprot ID
功能
Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.
化学信息
分子量Theoretical: 139 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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