购物车
- 全部删除
您的购物车当前为空
Anti-BUB1B Antibody (4Y527)
还可以产品编号 TMAH-00125
别名 Protein SSK1, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Mitotic checkpoint kinase MAD3L, MAD3/BUB1-related protein kinase, hBUBR1, EC 2.7.11.1, BUBR1 MAD3L SSK1, BUB 1B
Anti-BUB1B Antibody (4Y527) 是一种抗体，靶向 BUB1B。Anti-BUB1B Antibody (4Y527) 可用于 ELISA, WB, FC。
Anti-BUB1B Antibody (4Y527)
Anti-BUB1B Antibody (4Y527)
还可以产品编号 TMAH-00125 别名 Protein SSK1, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Mitotic checkpoint kinase MAD3L, MAD3/BUB1-related protein kinase, hBUBR1, EC 2.7.11.1, BUBR1 MAD3L SSK1, BUB 1B
Anti-BUB1B Antibody (4Y527) 是一种抗体，靶向 BUB1B。Anti-BUB1B Antibody (4Y527) 可用于 ELISA, WB, FC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-BUB1B Antibody (4Y527) is an antibody targeting BUB1B. Anti-BUB1B Antibody (4Y527) can be used in ELISA, WB, FC. |
| 别名 | Protein SSK1, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Mitotic checkpoint kinase MAD3L, MAD3/BUB1-related protein kinase, hBUBR1, EC 2.7.11.1, BUBR1 MAD3L SSK1, BUB 1B |
| Ig Type | Rabbit IgG |
| 克隆号 | 4Y527 |
| 交叉反应 | Human |
| 验证活性 | 1. Western Blot -Positive WB detected in: K562 whole cell lysate, U-251 whole cell lysate -All lanes: BubR1 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 120, 106, 122 kDa -Observed band size: 125 kDa 2. Overlay histogram showing Hela cells stained with TMAH-00125 (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1µg/1*10^6 cells) for 1 h at 4°C.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4°C. Control antibody (green line) was Rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| 应用 | ELISA, WB, FC |
| 推荐剂量 | WB:1:500-1:5000; FC:1:20-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in interphase cells. Associates with the kinetochores in early prophase. Kinetochore localization requires BUB1, PLK1 and KNL1. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. Negatively regulates PLK1 activity in interphase cells and suppresses centrosome amplification. Also implicated in triggering apoptosis in polyploid cells that exit aberrantly from mitotic arrest. May play a role for tumor suppression. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human BubR1 |
| 抗原种属 | Human |
| 基因ID | 701 |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Cancer, Cell biology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-BUB1B Antibody (4Y527) | purchase Anti-BUB1B Antibody (4Y527) | Anti-BUB1B Antibody (4Y527) cost | order Anti-BUB1B Antibody (4Y527)
嗨！有任何问题？点我咨询
评论内容