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Anti-PAX5 Antibody (9W709) 是一种 Rabbit 抗体,靶向 PAX5。Anti-PAX5 Antibody (9W709) 可用于 IHC-P,IHC-Fr,IF,FCM,ICC/IF。
Anti-PAX5 Antibody (9W709) 是一种 Rabbit 抗体,靶向 PAX5。Anti-PAX5 Antibody (9W709) 可用于 IHC-P,IHC-Fr,IF,FCM,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-PAX5 Antibody (9W709) is a Rabbit antibody targeting PAX5. Anti-PAX5 Antibody (9W709) can be used in IHC-P,IHC-Fr,IF,FCM,ICC/IF. |
| Ig Type | IgG |
| 克隆号 | 9W709 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | IHC-PIHC-FrIFFCMICC/IF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed at early B-cell differentiation, in the developing CNS and in adult testis. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
| 免疫原 | A synthesized peptide: human PAX5 |
| 抗原种属 | Human |
| 基因名称 | PAX5 |
| 基因ID | |
| 蛋白名称 | Paired box protein Pax-5 |
| Uniprot ID | |
| 功能 | May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. |
| 分子量 | Theoretical: 42 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |