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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PRAM1 Polyclonal Antibody

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货号 TMAB-11708

Anti-PRAM1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PRAM1。Anti-PRAM1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PRAM1 Polyclonal Antibody

Anti-PRAM1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11708

Anti-PRAM1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PRAM1。Anti-PRAM1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-PRAM1 Polyclonal Antibody is a Rabbit antibody targeting PRAM1. Anti-PRAM1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Expressed in peripheral blood leukocytes and bone marrow. Expressed in monocytes, and to a lesser extent in granulocytes and lymphocytes. Not expressed in non hematopoietic tissues except in lung.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells. The retinoic acid-induced gene, PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis. PRAM-1 expression is hindered by expression of PML-RAR-a. The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs. PRAM-1 demonstrates expression in hematopoietic tissues and lung.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PRAM1
抗原种属
Human
基因名称
PRAM1
基因ID
84106
蛋白名称
PML-RARA-regulated adapter molecule 1
Uniprot ID
Q96QH2
功能
May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P.
化学信息
分子量Theoretical: 79 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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