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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IL33 Antibody (2B332)

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货号 TMAB-07660

Anti-IL33 Antibody (2B332) 是一种 Rabbit 抗体，靶向 IL33。Anti-IL33 Antibody (2B332) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-IL33 Antibody (2B332)

Anti-IL33 Antibody (2B332)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07660

Anti-IL33 Antibody (2B332) 是一种 Rabbit 抗体，靶向 IL33。Anti-IL33 Antibody (2B332) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL33 Antibody (2B332) is a Rabbit antibody targeting IL33. Anti-IL33 Antibody (2B332) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
2B332
反应种属
Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome. Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Associates with heterochromatin and mitotic chromosomes. Translocation from the nucleus occurs upon biomechanical strain, depends on an intact microtubule network, and is ATP-dependent.
组织特异性Expressed at high level in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes. Almost undetectable in placenta.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells.Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines.
抗原信息
免疫原
A synthesized peptide: mouse IL 33
抗原种属
Mouse
基因名称
IL33
基因ID
77125
蛋白名称
Interleukin-33
Uniprot ID
Q8BVZ5
功能
Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T-helper type 2-associated cytokines. Acts as a chemoattractant tor Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation.
化学信息
分子量Theoretical: 30 kDa. Actual: 33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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