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Etoxazole

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纯度: 99.89%

货号 T4055Cas号 153233-91-1

别名 乙螨唑

Etoxazole 是一种杀螨剂/杀虫剂,通过抑制几丁质生物合成来控制螨虫。用作农药检测的标准。

Etoxazole
其他形式的 “Etoxazole”:

Etoxazole

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Rating icon 很棒

纯度: 99.89%

货号 T4055 别名 乙螨唑Cas号 153233-91-1

Etoxazole 是一种杀螨剂/杀虫剂,通过抑制几丁质生物合成来控制螨虫。用作农药检测的标准。

规格价格库存数量
5 mg
¥ 248
现货
10 mg
¥ 348
现货
25 mg
¥ 563
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50 mg
¥ 1,060
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100 mg
¥ 1,580
现货
500 mg
¥ 3,970
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1 mL x 10 mM (in DMSO)
¥ 297
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产品介绍


Etoxazole AI Summary
Etoxazole demonstrates a multifaceted profile of bioactivities across various biological systems and organisms. It functions as both an agonist and antagonist for multiple signaling pathways, including estrogen receptor alpha, peroxisome proliferator-activated receptor gamma, farnesoid X receptor, antioxidant response element, rat and human pregnane X receptor, and androgen receptor signaling pathways. In terms of pesticidal activity, Etoxazole exhibits potent insecticidal properties against several pests, achieving 100% mortality at 500 ppm for Myzus persicae (green peach aphid), Plutella xylostella (diamondback moth), and Nephotettix cincticeps (green rice leafhopper). It shows strong acaricidal activity against Tetranychus urticae (two-spotted spider mite) with an LC50 value of 0.001 ppm for larvicidal activity and causes mortality in eggs with an LC50 of 13.8 nM on compound-treated kidney bean leaves. Additionally, it demonstrates efficacy against Panonychus ulmi larvae with LC50 values of 0.15 ug/mL and greater than 10000.0 ug/mL for different strains, indicating a notable insecticidal potency particularly against resistant strains. Additional experiments highlight its impact on bumblebee workers (Bombus terrestris), with a NOAEL of 0.55 mgAi/L and LC50 of 4.4 mgAi/L when administered through sugar water over 11 weeks. A striking reduction in reproductive activity and high mortality rates are observed at concentrations of 55 mg a.i./l when delivered via pollen (25% reproductive reduction) and sugar water (95% mortality), respectively. However, topical application at the same concentration results in less than 25% mortality over the same period. Moreover, Etoxazole exhibits activity against spirodiclofen-resistant and susceptible Tetranychus urticae larvae, with LC50 values of 0.61 ug/mL for resistant and 0.76 ug/mL for susceptible larvae, suggesting slight variability in efficacy between resistant and susceptible strains. Overall, Etoxazole is characterized by its versatile bioactivity and marked efficacy in pest control applications..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Etoxazole is an acaricide/insecticide that works via chitin biosynthesis inhibition for the control of mites. Used as a standard for Pesticide detection.
别名乙螨唑
化学信息
分子量359.41
分子式C21H23F2NO2
CAS No.153233-91-1
SmilesCCOc1cc(ccc1C1COC(=N1)c1c(F)cccc1F)C(C)(C)C
密度1.15g/cm3
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度信息
DMSO: 50 mg/mL (139.12 mM), Sonication is recommended.
体内实验配方
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 1.67 mg/mL (4.65 mM), Sonication is recommended.
请按顺序添加溶剂,在添加下一种溶剂之前,尽可能使溶液澄清。如有必要,可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考,体内配方并不是绝对的,请根据不同情况进行调整。
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM2.7823 mL13.9117 mL27.8234 mL139.1169 mL
5 mM0.5565 mL2.7823 mL5.5647 mL27.8234 mL
10 mM0.2782 mL1.3912 mL2.7823 mL13.9117 mL
20 mM0.1391 mL0.6956 mL1.3912 mL6.9558 mL
50 mM0.0556 mL0.2782 mL0.5565 mL2.7823 mL
100 mM0.0278 mL0.1391 mL0.2782 mL1.3912 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL, 一共给药动物10只,您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O, 那么您的工作液浓度为2 mg/mL
母液配置方法:2 mg 药物溶于 100 μL DMSO ( 母液浓度为 20 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:100 μL DMSO 母液, 添加 400 μL PEG300 混匀澄清, 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如: DMSOPEG300PEG400Tween 80SBE-β-CD玉米油等, 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

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