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Etoxazole

Synonyms: 乙螨唑
货号 T4055Cas号 153233-91-1 一键复制产品信息 纯度: 99.94%
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Etoxazole 是一种杀螨剂/杀虫剂,通过抑制几丁质生物合成来控制螨虫。用作农药检测的标准。

Etoxazole

一键复制产品信息
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纯度: 99.94%

货号 T4055Cas号 153233-91-1

别名 乙螨唑

Etoxazole 是一种杀螨剂/杀虫剂,通过抑制几丁质生物合成来控制螨虫。用作农药检测的标准。

Etoxazole
其他形式的 “Etoxazole”:
规格价格库存数量
5 mg
¥ 248
现货
10 mg
¥ 348
现货
25 mg
¥ 563
现货
50 mg
¥ 1,060
现货
100 mg
¥ 1,580
现货
500 mg
¥ 3,970
现货
1 mL x 10 mM (in DMSO)
¥ 297
现货
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纯度: 99.94%
性状: Solid

产品介绍


Etoxazole AI Summary
Etoxazole demonstrates a multifaceted profile of bioactivities across various biological systems and organisms. It functions as both an agonist and antagonist for multiple signaling pathways, including estrogen receptor alpha, peroxisome proliferator-activated receptor gamma, farnesoid X receptor, antioxidant response element, rat and human pregnane X receptor, and androgen receptor signaling pathways. In terms of pesticidal activity, Etoxazole exhibits potent insecticidal properties against several pests, achieving 100% mortality at 500 ppm for Myzus persicae (green peach aphid), Plutella xylostella (diamondback moth), and Nephotettix cincticeps (green rice leafhopper). It shows strong acaricidal activity against Tetranychus urticae (two-spotted spider mite) with an LC50 value of 0.001 ppm for larvicidal activity and causes mortality in eggs with an LC50 of 13.8 nM on compound-treated kidney bean leaves. Additionally, it demonstrates efficacy against Panonychus ulmi larvae with LC50 values of 0.15 ug/mL and greater than 10000.0 ug/mL for different strains, indicating a notable insecticidal potency particularly against resistant strains. Additional experiments highlight its impact on bumblebee workers (Bombus terrestris), with a NOAEL of 0.55 mgAi/L and LC50 of 4.4 mgAi/L when administered through sugar water over 11 weeks. A striking reduction in reproductive activity and high mortality rates are observed at concentrations of 55 mg a.i./l when delivered via pollen (25% reproductive reduction) and sugar water (95% mortality), respectively. However, topical application at the same concentration results in less than 25% mortality over the same period. Moreover, Etoxazole exhibits activity against spirodiclofen-resistant and susceptible Tetranychus urticae larvae, with LC50 values of 0.61 ug/mL for resistant and 0.76 ug/mL for susceptible larvae, suggesting slight variability in efficacy between resistant and susceptible strains. Overall, Etoxazole is characterized by its versatile bioactivity and marked efficacy in pest control applications..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Etoxazole is an acaricide/insecticide that works via chitin biosynthesis inhibition for the control of mites. Used as a standard for Pesticide detection.
别名乙螨唑
化学信息
分子量359.41
分子式C21H23F2NO2
CAS No.153233-91-1
SmilesCCOc1cc(ccc1C1COC(=N1)c1c(F)cccc1F)C(C)(C)C
密度1.15g/cm3
储存&溶解度
存储
溶解度信息
DMSO: 50 mg/mL (139.12 mM), Sonication is recommended.
体内实验配方
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 1.67 mg/mL (4.65 mM), Sonication is recommended.
请按顺序添加溶剂,在添加下一种溶剂之前,尽可能使溶液澄清。如有必要,可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考,体内配方并不是绝对的,请根据不同情况进行调整。
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM2.7823 mL13.9117 mL27.8234 mL139.1169 mL
5 mM0.5565 mL2.7823 mL5.5647 mL27.8234 mL
10 mM0.2782 mL1.3912 mL2.7823 mL13.9117 mL
20 mM0.1391 mL0.6956 mL1.3912 mL6.9558 mL
50 mM0.0556 mL0.2782 mL0.5565 mL2.7823 mL
100 mM0.0278 mL0.1391 mL0.2782 mL1.3912 mL
该溶液配制表仅适用于固体产品。对于液体产品,请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL, 一共给药动物10只,您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O, 那么您的工作液浓度为2 mg/mL
母液配置方法:2 mg 药物溶于 100 μL DMSO ( 母液浓度为 20 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:100 μL DMSO 母液, 添加 400 μL PEG300 混匀澄清, 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如: DMSOPEG300PEG400Tween 80SBE-β-CD玉米油等, 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

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