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Anti-GERP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GERP。Anti-GERP Polyclonal Antibody 可用于 WB。
Anti-GERP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GERP。Anti-GERP Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-GERP Polyclonal Antibody is a Rabbit antibody targeting GERP. Anti-GERP Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Chicken,Dog,Horse,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 组织特异性 | Widely expressed. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM8 (tripartite motif containing 8), also known as GERP (glioblastoma-expressed RING finger protein) or RNF27 (RING finger protein 27), is a 551 amino acid protein that is thought to function as an E3 ubiquitin-protein ligase that promotes SOCS-1 proteasomal degradation. As a widely expressed homodimer, TRIM8 localizes to nuclear bodies and contains two B box-type zinc fingers and one RING-type zinc finger. TRIM8 is expressed in lung, heart, brain and skeletal muscle, with low levels detected in intestine, placenta, leukocytes and liver. The gene encoding TRIM8 maps to human chromosome 10q24.32. |
| 免疫原 | KLH conjugated synthetic peptide: human GERP/TRIM8/RNF27 |
| 抗原种属 | Human |
| 基因名称 | TRIM8 |
| 基因ID | |
| 蛋白名称 | E3 ubiquitin-protein ligase TRIM8 |
| Uniprot ID | |
| 功能 | Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1. |
| 分子量 | Theoretical: 61 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |