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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Kir6.2 Polyclonal Antibody

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货号 TMAB-08078

Anti-Kir6.2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Kir6.2。Anti-Kir6.2 Polyclonal Antibody 可用于 WB,FCM。

Anti-Kir6.2 Polyclonal Antibody

Anti-Kir6.2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08078

Anti-Kir6.2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Kir6.2。Anti-Kir6.2 Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Kir6.2 Polyclonal Antibody is a Rabbit antibody targeting Kir6.2. Anti-Kir6.2 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Cow,Rabbit)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane; Multi-pass membrane protein
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Kir62
抗原种属
Human
基因名称
KCNJ11
基因ID
3767
蛋白名称
ATP-sensitive inward rectifier potassium channel 11
Uniprot ID
Q14654
功能
ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus.
化学信息
分子量Theoretical: 43 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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