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Anti-S100A16 Antibody (7D573)
还可以产品编号 TMAY-01673
Anti-S100A16 Antibody (7D573) 是一种 Rabbit 抗体，靶向 S100A16。Anti-S100A16 Antibody (7D573) 可用于 ELISA。
Anti-S100A16 Antibody (7D573)
Anti-S100A16 Antibody (7D573)
还可以产品编号 TMAY-01673
Anti-S100A16 Antibody (7D573) 是一种 Rabbit 抗体，靶向 S100A16。Anti-S100A16 Antibody (7D573) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-S100A16 Antibody (7D573) is a Rabbit antibody targeting S100A16. Anti-S100A16 Antibody (7D573) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7D573 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human S100A16 (rh S100A16; TMPY-02135; Q96FQ6; Met1-Ser103). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has been obtained both in the solid state and in solution, resulting in good agreement between the structures with the exception of two loop regions. The homodimeric solution structure of human S100A16 was also calculated in the calcium(II)-bound form. Differently from most S100 proteins, the conformational rearrangement upon calcium binding is minor. Immunoprecipitation analysis revealed that S100A16 could physically interact with tumor suppressor protein p53, also a known inhibitor of adipogenesis. Overexpression or RNA interference-initiated reduction of S100A16 led to the inhibition or activation of the expression of p53-responsive genes, respectively. S100A16 protein is a novel adipogenesis-promoting factor and that increased expression of S100A16 in 3T3-L1 adipocytes can have a negative impact on insulin sensitivity. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human S100A16 protein (TMPY-02135) |
| 抗原种属 | Human |
| 研究领域 | Calcium-binding Proteins and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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