Name: TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-07144
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 387

3日内发货

10 μg

¥ 623

3日内发货

20 μg

¥ 987

3日内发货

50 μg

¥ 1,970

3日内发货

100 μg

¥ 3,390

现货

200 μg

¥ 5,720

5日内发货

500 μg

¥ 11,500

5日内发货

1 mg

¥ 19,500

5日内发货

生物活性

产品描述	TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is O95150-1.
生物活性	1. Immobilized Human TNFSF15, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human DR3, hFc Tag with the EC50 of 0.19 μg/ml determined by ELISA. (QC Test) 2. Immobilized Human TNFSF15, His Tag at 1 μg/ml(100 μl/well) on the plate. Dose response curve for Human DcR3, hFc Tag with the EC50 of 24.2 ng/ml determined by ELISA. 3. Immobilized Human TNFSF15, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 3.8 ng/ml determined by ELISA 4. Human DR3, hFc Tag captured on CM5 Chip via Protein A can bind Human TNFSF15, His Tag with an affinity constant of 4.09 nM as determined in SPR assay (Biacore T200). 5. Loaded Human DR3, hFc Tag on ProA-Biosensor, can bind Human TNFSF15, His Tag with an affinity constant of 5.04 nM as determined in BLI assay (Gator).
研究背景	TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. TL1A is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It mediates activation of NF-kappa-B. It also inhibits vascular endothelial growth and angiogenesis (in vitro). TL1A promotes activation of caspases and apoptosis. It is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
种属	Human
表达系统	HEK293 Cells
标签	N-His
蛋白编号	O95150-1
蛋白构建	Leu72-Leu251
蛋白纯度	> 90% as determined by Bis-Tris PAGE
缓冲液	Lyophilized from 0.22 μm filtered solution in 20 mM PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	VEGI192A, VEGI, TNLG1B, TL1A, TL1, MGC129935, MGC129934
内毒素	< 1.0 EU per μg of the protein as determined by the LAL method

化学信息

分子量	25-35 kDa (reducing contition, due to glycosylation); 60-90 kDa (SEC-MALS)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His)

TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His)

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