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NGF Protein, Human, Recombinant

NGF Protein, Human, Recombinant

产品编号 TMPY-01010
别名: Beta-NGF, 神经生长因子, β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5

NGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 13.2 kDa and the accession number is P01138.

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TargetMol
NGF Protein, Human, Recombinant
规格 价格/CNY 货期 数量
100 μg ¥ 1,550 现货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: NGF Protein, Human, Recombinant (TMPY-01010)
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生物活性
技术参数
产品性质
参考文献
生物活性 Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2-2 ng/ml.

TargetMol Bioactive

产品描述 NGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 13.2 kDa and the accession number is P01138.
种属 Human
表达系统 CHO Cells
标签 Tag Free
蛋白编号 P01138
别名 Beta-NGF, 神经生长因子, β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5
蛋白构建 mature form of Human β-NGF (NP_002497.2) (Ser 122-Arg 239)
蛋白纯度 > 95 % as determined by SDS-PAGE

TargetMol

分子量 13.2 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 40 mM His, 40 mM Arg, 150 mM NaCl, pH 5. 5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.

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Keywords

NGF Protein, Human, Recombinant Beta-NGF nerve growth factor 神经生长因子 β-NGF β polypeptide NGFB HSAN-5 nerve growth factor (β polypeptide) b-NGF nerve growth factor (beta polypeptide) HSAN5 beta polypeptide HSAN 5 b polypeptide recombinant recombinant-proteins proteins protein

 

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