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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-p47/Pleckstrin Polyclonal Antibody

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货号 TMAB-09872

Anti-p47/Pleckstrin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 p47/Pleckstrin。Anti-p47/Pleckstrin Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-p47/Pleckstrin Polyclonal Antibody

Anti-p47/Pleckstrin Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09872

Anti-p47/Pleckstrin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 p47/Pleckstrin。Anti-p47/Pleckstrin Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-p47/Pleckstrin Polyclonal Antibody is a Rabbit antibody targeting p47/Pleckstrin. Anti-p47/Pleckstrin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Cow,Horse,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Golgi apparatus > Golgi stack. Chromosome. Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks.
组织特异性Major protein kinase C substrate of platelets.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Platelet P47, also known as NSFL1C, UBX1, UBXD10 or UBXN2C, is a 370 amino acid protein that localizes to both the nucleus and the golgi apparatus (specifically to golgi stacks) and contains one SEP domain and one UBX domain. Functioning as part of a ternary complex with VCP (a protein involved in the heterotypic fusion of transport vesicles with their target membranes) and Syntaxin 5, p47 interacts with and reduces the ATPase activity of VCP and is required for the fragmentation of golgi stacks during mitosis and for subsequent reassembly of golgi stacks after mitosis. p47 is subject to phosphorylation during mitosis, which inhibits p47-golgi interaction and is, therefore, required for proper golgi stack formation and cisternal regrowth. Human p47 shares 89% sequence identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of p47 exist due to alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Pleckstrin
抗原种属
Human
基因名称
NSFL1C
基因ID
5341
蛋白名称
NSFL1 cofactor p47
Uniprot ID
P08567
功能
Major protein kinase C substrate of platelets.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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